| 2019-09-15 15:00:00September 15, 2019 | Salford Red Devils  | - |  Hull Kingston Rovers | 15:00:003:00 pm |
| 2019-09-06 19:45:00September 6, 2019 | Leeds Rhinos  | - | Salford Red Devils | 19:45:007:45 pm |
| 2019-09-01 15:00:00September 1, 2019 | Salford Red Devils | - |  Warrington Wolves | 15:00:003:00 pm |
| 2019-08-17 17:00:00August 17, 2019 | Hull FC  | - | Salford Red Devils | 17:00:005:00 pm |
| 2019-08-11 15:00:00August 11, 2019 | Salford Red Devils | - |  Huddersfield Giants | 15:00:003:00 pm |
| 2019-08-04 15:00:00August 4, 2019 | London Broncos  | - | Salford Red Devils | 15:00:003:00 pm |
| 2019-07-21 15:00:00July 21, 2019 | Salford Red Devils | - |  Catalans Dragons | 15:00:003:00 pm |
| 2019-07-12 19:45:00July 12, 2019 | Warrington Wolves | - | Salford Red Devils | 19:45:007:45 pm |
| 2019-07-04 19:45:00July 4, 2019 | Salford Red Devils | - | Huddersfield Giants | 19:45:007:45 pm |
| 2019-06-28 19:45:00June 28, 2019 | Wigan Warriors  | - | Salford Red Devils | 19:45:007:45 pm |
| 2019-06-21 19:45:00June 21, 2019 | Salford Red Devils | - |  Castleford Tigers | 19:45:007:45 pm |
| 2019-06-16 15:00:00June 16, 2019 | Salford Red Devils | - |  Wakefield Trinity | 15:00:003:00 pm |
| 2019-06-07 19:45:00June 7, 2019 | Hull FC | - | Salford Red Devils | 19:45:007:45 pm |
| 2019-05-26 13:00:00May 26, 2019 | Salford Red Devils | - | Hull Kingston Rovers | 13:00:001:00 pm |
| 2019-05-17 19:45:00May 17, 2019 | St Helens  | 32 - 30 | Salford Red Devils | 19:45:007:45 pm |
| 2019-05-03 19:45:00May 3, 2019 | Salford Red Devils | 28 - 16 | Leeds Rhinos | 19:45:007:45 pm |
| 2019-04-27 15:00:00April 27, 2019 | London Broncos | 10 - 30 | Salford Red Devils | 15:00:003:00 pm |
| 2019-04-22 15:00:00April 22, 2019 | Salford Red Devils | 26 - 30 | Wigan Warriors | 15:00:003:00 pm |
| 2019-04-19 15:00:00April 19, 2019 | Warrington Wolves | 12 - 36 | Salford Red Devils | 15:00:003:00 pm |
| 2019-04-07 15:00:00April 7, 2019 | Salford Red Devils | 16 - 23 | Hull FC | 15:00:003:00 pm |
| 2019-03-31 15:00:00March 31, 2019 | Wakefield Trinity | 33 - 22 | Salford Red Devils | 15:00:003:00 pm |
| 2019-03-24 15:00:00March 24, 2019 | Salford Red Devils | 22 - 30 | Wigan Warriors | 15:00:003:00 pm |
| 2019-03-17 15:30:00March 17, 2019 | Castleford Tigers | 24 - 20 | Salford Red Devils | 15:30:003:30 pm |
| 2019-03-09 18:00:00March 9, 2019 | Catalans Dragons | 0 - 46 | Salford Red Devils | 18:00:006:00 pm |
| 2019-02-28 19:45:00February 28, 2019 | Salford Red Devils | 4 - 26 | St Helens | 19:45:007:45 pm |
| 2019-02-23 15:00:00February 23, 2019 | Hull Kingston Rovers | 22 - 24 | Salford Red Devils | 15:00:003:00 pm |
| 2019-02-17 15:00:00February 17, 2019 | Salford Red Devils | 14 - 46 | Leeds Rhinos | 15:00:003:00 pm |
| 2019-02-10 15:00:00February 10, 2019 | Salford Red Devils | 24 - 0 | London Broncos | 15:00:003:00 pm |
| 2019-02-01 19:45:00February 1, 2019 | Huddersfield Giants | 14 - 34 | Salford Red Devils | 19:45:007:45 pm |
| 2018-09-27 19:45:00September 27, 2018 | Salford Red Devils | 44 - 10 |  Toulouse Olympique | 19:45:007:45 pm |
| 2018-09-23 15:00:00September 23, 2018 | London Broncos | 11 - 8 | Salford Red Devils | 15:00:003:00 pm |
| 2018-09-14 19:45:00September 14, 2018 | Leeds Rhinos | 18 - 16 | Salford Red Devils | 19:45:007:45 pm |
| 2018-09-08 15:15:00September 8, 2018 | Salford Red Devils | 28 - 16 |  Toronto Wolfpack | 15:15:003:15 pm |
| 2018-09-02 15:00:00September 2, 2018 | Halifax RLFC  | 4 - 62 | Salford Red Devils | 15:00:003:00 pm |
| 2018-08-18 15:15:00August 18, 2018 | Salford Red Devils | 32 - 6 |  Widnes Vikings | 15:15:003:15 pm |
| 2018-08-10 20:00:00August 10, 2018 | Hull Kingston Rovers | 10 - 28 | Salford Red Devils | 20:00:008:00 pm |
| 2018-07-27 19:30:00July 27, 2018 | Salford Red Devils | 38 - 22 | Leeds Rhinos | 19:30:007:30 pm |
| 2018-07-21 18:00:00July 21, 2018 | Catalans Dragons | 44 - 10 | Salford Red Devils | 18:00:006:00 pm |
| 2018-07-13 19:30:00July 13, 2018 | Salford Red Devils | 6 - 24 | Castleford Tigers | 19:30:007:30 pm |
| 2018-07-08 15:00:00July 8, 2018 | Hull Kingston Rovers | 52 - 22 | Salford Red Devils | 15:00:003:00 pm |
| 2018-06-29 19:45:00June 29, 2018 | Warrington Wolves | 30 - 14 | Salford Red Devils | 19:45:007:45 pm |
| 2018-06-14 19:45:00June 14, 2018 | Salford Red Devils | 26 - 12 | Widnes Vikings | 19:45:007:45 pm |
| 2018-06-08 20:00:00June 8, 2018 | Hull FC | 45 - 14 | Salford Red Devils | 20:00:008:00 pm |
| 2018-05-25 19:30:00May 25, 2018 | Salford Red Devils | 16 - 24 | Huddersfield Giants | 19:30:007:30 pm |
| 2018-05-20 13:00:00May 20, 2018 | Salford Red Devils | 12 - 26 | Catalans Dragons | 13:00:001:00 pm |
| 2018-05-06 15:00:00May 6, 2018 | Wigan Warriors | 30 - 0 | Salford Red Devils | 15:00:003:00 pm |
| 2018-04-26 19:45:00April 26, 2018 | Salford Red Devils | 10 - 60 | St Helens | 19:45:007:45 pm |
| 2018-04-20 19:30:00April 20, 2018 | Salford Red Devils | 38 - 4 | Wakefield Trinity | 19:30:007:30 pm |
| 2018-04-15 15:00:00April 15, 2018 | Huddersfield Giants | 12 - 30 | Salford Red Devils | 15:00:003:00 pm |
| 2018-04-07 15:15:00April 7, 2018 | Salford Red Devils | 6 - 22 | Warrington Wolves | 15:15:003:15 pm |
| 2018-04-02 15:00:00April 2, 2018 | Leeds Rhinos | 20 - 0 | Salford Red Devils | 15:00:003:00 pm |
| 2018-03-30 12:00:00March 30, 2018 | Salford Red Devils | 32 - 16 | Catalans Dragons | 12:00:0012:00 pm |
| 2018-03-22 19:45:00March 22, 2018 | Widnes Vikings | 24 - 16 | Salford Red Devils | 19:45:007:45 pm |
| 2018-03-16 20:00:00March 16, 2018 | Salford Red Devils | 24 - 8 | Hull FC | 20:00:008:00 pm |
| 2018-03-11 15:30:00March 11, 2018 | Castleford Tigers | 22 - 8 | Salford Red Devils | 15:30:003:30 pm |
| 2018-03-04 15:00:00March 4, 2018 | St Helens | 34 - 2 | Salford Red Devils | 15:00:00Postponed |
| 2018-02-23 19:30:00February 23, 2018 | Salford Red Devils | 36 - 12 | Hull Kingston Rovers | 19:30:007:30 pm |
| 2018-02-09 19:45:00February 9, 2018 | Wakefield Trinity | 14 - 12 | Salford Red Devils | 19:45:007:45 pm |
| 2018-02-02 19:30:00February 2, 2018 | Salford Red Devils | 12 - 40 | Wigan Warriors | 19:30:007:30 pm |
