| 2022-03-11 19:05:59March 11, 2022 | Broncos   |   Rabbitohs | 19:05:5919:05 | Telstra National Rugby League Premiership | 2022 | |
| 2022-03-17 20:05:00March 17, 2022 | Storm  | Rabbitohs | 20:05:0020:05 | Telstra National Rugby League Premiership | 2022 | |
| 2022-03-25 20:05:00March 25, 2022 | Rabbitohs |  Roosters | 20:05:0020:05 | Telstra National Rugby League Premiership | 2022 | |
| 2022-04-01 20:05:00April 1, 2022 | Panthers   | Rabbitohs | 20:05:0020:05 | Telstra National Rugby League Premiership | 2022 | |
| 2022-04-09 17:30:00April 9, 2022 | Rabbitohs |   Dragons | 17:30:0017:30 | Telstra National Rugby League Premiership | 2022 | |
| 2022-04-15 16:00:00April 15, 2022 | Rabbitohs |   Bulldogs | 16:00:0016:00 | Telstra National Rugby League Premiership | 2022 | |
| 2022-04-23 19:35:00April 23, 2022 | Tigers   | Rabbitohs | 19:35:0019:35 | Telstra National Rugby League Premiership | 2022 | |
| 2022-04-29 19:55:00April 29, 2022 | Rabbitohs |   Sea Eagles | 19:55:0019:55 | Telstra National Rugby League Premiership | 2022 | |
| 2022-05-05 19:50:00May 5, 2022 | Rabbitohs | Broncos | 19:50:0019:50 | Telstra National Rugby League Premiership | 2022 | |
| 2022-05-14 15:00:28May 14, 2022 | Warriors   | Rabbitohs | 15:00:2815:00 | Telstra National Rugby League Premiership | 2022 | |
| 2022-05-22 14:00:00May 22, 2022 | Rabbitohs |  Raiders | 14:00:0014:00 | Telstra National Rugby League Premiership | 2022 | |
| 2022-05-28 17:30:00May 28, 2022 | Rabbitohs | Tigers | 17:30:0017:30 | Telstra National Rugby League Premiership | 2022 | |
| 2022-06-11 15:00:00June 11, 2022 | Titans   | Rabbitohs | 15:00:0015:00 | Telstra National Rugby League Premiership | 2022 | |
| 2022-06-16 19:50:00June 16, 2022 | Dragons | Rabbitohs | 19:50:0019:50 | Telstra National Rugby League Premiership | 2022 | |
| 2022-07-02 19:35:00July 2, 2022 | Rabbitohs |  Eels | 19:35:0019:35 | Telstra National Rugby League Premiership | 2022 | |
| 2022-07-08 19:55:00July 8, 2022 | Knights   | Rabbitohs | 19:55:0019:55 | Telstra National Rugby League Premiership | 2022 | |
| 2022-07-18 18:15:00July 18, 2022 | Bulldogs | Rabbitohs | 18:15:0018:15 | Telstra National Rugby League Premiership | 2022 | |
| 2022-07-23 19:35:00July 23, 2022 | Rabbitohs | Storm | 19:35:0019:35 | Telstra National Rugby League Premiership | 2022 | |
| 2022-07-30 17:30:00July 30, 2022 | Sharks   | Rabbitohs | 17:30:0017:30 | Telstra National Rugby League Premiership | 2022 | |
| 2022-08-06 15:00:00August 6, 2022 | Rabbitohs | Warriors | 15:00:0015:00 | Telstra National Rugby League Premiership | 2022 | |
| 2022-08-12 19:55:00August 12, 2022 | Eels | Rabbitohs | 19:55:0019:55 | Telstra National Rugby League Premiership | 2022 | |
| 2022-08-18 19:50:00August 18, 2022 | Rabbitohs | Panthers | 19:50:0019:50 | Telstra National Rugby League Premiership | 2022 | |
| 2022-08-27 19:35:00August 27, 2022 | Rabbitohs |   Cowboys | 19:35:0019:35 | Telstra National Rugby League Premiership | 2022 | |
| 2022-09-02 19:55:00September 2, 2022 | Roosters | Rabbitohs | 19:55:0019:55 | Telstra National Rugby League Premiership | 2022 | |
