| 2018-09-15 19:40:00September 15, 2018 | South Sydney Rabbitohs  | 13 - 12 |  St George-Illawarra Dragons | 19:40:007:40 pm | N/A |
| 2018-09-09 16:00:00September 9, 2018 | Brisbane Broncos  | 18 - 48 | St George-Illawarra Dragons | 16:00:004:00 pm | N/A |
| 2018-09-01 15:00:00September 1, 2018 | Newcastle Knights  | 14 - 24 | St George-Illawarra Dragons | 15:00:003:00 pm | N/A |
| 2018-08-26 16:10:00August 26, 2018 | St George-Illawarra Dragons | 0 - 38 |  Canterbury Bulldogs | 16:10:004:10 pm | N/A |
| 2018-08-18 17:30:00August 18, 2018 | Wests Tigers  | 10 - 20 | St George-Illawarra Dragons | 17:30:005:30 pm | N/A |
| 2018-08-11 19:30:00August 11, 2018 | Parramatta Eels  | 40 - 4 | St George-Illawarra Dragons | 19:30:007:30 pm | N/A |
| 2018-08-04 15:00:00August 4, 2018 | St George-Illawarra Dragons | 12 - 18 |  New Zealand Warriors | 15:00:003:00 pm | N/A |
| 2018-07-29 16:10:00July 29, 2018 | Sydney Roosters  | 36 - 18 | St George-Illawarra Dragons | 16:10:004:10 pm | N/A |
| 2018-07-21 19:30:00July 21, 2018 | North Queensland Cowboys  | 10 - 24 | St George-Illawarra Dragons | 19:30:007:30 pm | N/A |
| 2018-07-15 16:10:00July 15, 2018 | St George-Illawarra Dragons | 16 - 20 | Wests Tigers | 16:10:004:10 pm | N/A |
| 2018-07-05 19:50:00July 5, 2018 | Melbourne Storm  | 52 - 30 | St George-Illawarra Dragons | 19:50:007:50 pm | N/A |
| 2018-06-16 17:30:00June 16, 2018 | St George-Illawarra Dragons | 32 - 8 |  Manly Sea Eagles | 17:30:005:30 pm | N/A |
| 2018-06-11 16:00:00June 11, 2018 | Canterbury Bulldogs | 16 - 18 | St George-Illawarra Dragons | 16:00:004:00 pm | N/A |
| 2018-05-26 19:30:00May 26, 2018 | Penrith Panthers  | 28 - 2 | St George-Illawarra Dragons | 19:30:007:30 pm | N/A |
| 2018-05-20 14:00:00May 20, 2018 | St George-Illawarra Dragons | 25 - 18 |  Canberra Raiders | 14:00:002:00 pm | N/A |
| 2018-05-13 14:00:00May 13, 2018 | South Sydney Rabbitohs | 24 - 10 | St George-Illawarra Dragons | 14:00:002:00 pm | N/A |
| 2018-05-06 14:00:00May 6, 2018 | St George-Illawarra Dragons | 34 - 14 | Melbourne Storm | 14:00:002:00 pm | N/A |
| 2018-04-25 16:10:00April 25, 2018 | St George-Illawarra Dragons | 24 - 8 | Sydney Roosters | 16:10:004:10 pm | N/A |
| 2018-04-20 18:00:00April 20, 2018 | New Zealand Warriors | 20 - 12 | St George-Illawarra Dragons | 18:00:006:00 pm | N/A |
| 2018-04-13 19:50:00April 13, 2018 | St George-Illawarra Dragons | 40 - 20 |  Cronulla Sharks | 19:50:007:50 pm | N/A |
| 2018-04-06 19:50:00April 6, 2018 | St George-Illawarra Dragons | 16 - 12 | South Sydney Rabbitohs | 19:50:007:50 pm | N/A |
| 2018-04-01 16:10:00April 1, 2018 | St George-Illawarra Dragons | 30 - 12 | Newcastle Knights | 16:10:004:10 pm | N/A |
| 2018-03-25 15:10:00March 25, 2018 | Gold Coast Titans  | 8 - 54 | St George-Illawarra Dragons | 15:10:003:10 pm | N/A |
| 2018-03-15 20:05:00March 15, 2018 | Cronulla Sharks | 16 - 20 | St George-Illawarra Dragons | 20:05:008:05 pm | N/A |
| 2018-03-08 20:05:00March 8, 2018 | St George-Illawarra Dragons | 34 - 12 | Brisbane Broncos | 20:05:008:05 pm | N/A |
